The study of chromatin structure and function is one of the most dynamic and
exciting fields in biology today. Check back often for summaries and discussion
of the latest breakthroughs in chromatin biology and epigenetics.

1.H2AX prevents CtIP-mediated DNA end resection and aberrant repair in G1-phase lymphocytes.
Helmink BA, Tubbs AT, Dorsett Y, Bednarski JJ, Walker LM, Feng Z, Sharma GG, McKinnon PJ, Zhang J, Bassing CH, Sleckman BP.
Nature. 2010 Dec 15. [Epub ahead of print]
PMID: 21160476 [PubMed - as supplied by publisher]

2.A unique chromatin signature uncovers early developmental enhancers in humans.
Rada-Iglesias A, Bajpai R, Swigut T, Brugmann SA, Flynn RA, Wysocka J.
Nature. 2010 Dec 15. [Epub ahead of print]
PMID: 21160473 [PubMed - as supplied by publisher]

3.ATM damage response and XLF repair factor are functionally redundant in joining DNA breaks.
Zha S, Guo C, Boboila C, Oksenych V, Cheng HL, Zhang Y, Wesemann DR, Yuen G, Patel H, Goff PH, Dubois RL, Alt FW.
Nature. 2010 Dec 15. [Epub ahead of print]
PMID: 21160472 [PubMed - as supplied by publisher]

4.Rotational position of a 5-methylcytosine-containing cyclobutane pyrimidine dimer in a nucleosome greatly affects its deamination rate.
Song Q, Cannistraro VJ, Taylor JS.
J Biol Chem. 2010 Dec 15. [Epub ahead of print]
PMID: 21160086 [PubMed - as supplied by publisher]

5.Prmt5 is essential for early mouse development and acts in the cytoplasm to maintain ES cell pluripotency.
Tee WW, Pardo M, Theunissen TW, Yu L, Choudhary JS, Hajkova P, Surani MA.
Genes Dev. 2010 Dec 15;24(24):2772-7.
PMID: 21159818 [PubMed - in process]

6.Gcn5 regulates the dissociation of SWI/SNF from chromatin by acetylation of Swi2/Snf2.
Kim JH, Saraf A, Florens L, Washburn M, Workman JL.
Genes Dev. 2010 Dec 15;24(24):2766-71.
PMID: 21159817 [PubMed - in process]

7.Histone H3 Lysine 79 Methyltransferase Dot1 Is Required for Immortalization by MLL Oncogenes.
Chang MJ, Wu H, Achille NJ, Reisenauer MR, Chou CW, Zeleznik-Le NJ, Hemenway CS, Zhang W.
Cancer Res. 2010 Dec 15;70(24):10234-10242.
PMID: 21159644 [PubMed - as supplied by publisher]

8.Epigenetic engineering shows H3K4me2 is required for HJURP targeting and CENP-A assembly on a synthetic human kinetochore.
Bergmann JH, Rodríguez MG, Martins NM, Kimura H, Kelly DA, Masumoto H, Larionov V, Jansen LE, Earnshaw WC.
EMBO J. 2010 Dec 14. [Epub ahead of print]
PMID: 21157429 [PubMed - as supplied by publisher]

9.Epigenetic suppression of the TGF-beta pathway revealed by transcriptome profiling in ovarian cancer.
Matsumura N, Huang Z, Mori S, Baba T, Fujii S, Konishi I, Iversen ES, Berchuck A, Murphy SK.
Genome Res. 2010 Dec 14. [Epub ahead of print]
PMID: 21156726 [PubMed - as supplied by publisher]

10.LIF-independent JAK signalling to chromatin in embryonic stem cells uncovered from an adult stem cell disease.
Griffiths DS, Li J, Dawson MA, Trotter MW, Cheng YH, Smith AM, Mansfield W, Liu P, Kouzarides T, Nichols J, Bannister AJ, Green AR, Göttgens B.
Nat Cell Biol. 2010 Dec 12. [Epub ahead of print]
PMID: 21151131 [PubMed - as supplied by publisher]

11.A methylation and phosphorylation switch between an adjacent lysine and serine determines human DNMT1 stability.
Estève PO, Chang Y, Samaranayake M, Upadhyay AK, Horton JR, Feehery GR, Cheng X, Pradhan S.
Nat Struct Mol Biol. 2010 Dec 12. [Epub ahead of print]
PMID: 21151116 [PubMed - as supplied by publisher]

12.Dicer associates with chromatin to repress genome activity in Schizosaccharomyces pombe.
Woolcock KJ, Gaidatzis D, Punga T, Bühler M.
Nat Struct Mol Biol. 2010 Dec 12. [Epub ahead of print]
PMID: 21151114 [PubMed - as supplied by publisher]

13.CENP-B preserves genome integrity at replication forks paused by retrotransposon LTR.
Zaratiegui M, Vaughn MW, Irvine DV, Goto D, Watt S, Bähler J, Arcangioli B, Martienssen RA.
Nature. 2010 Dec 12. [Epub ahead of print]
PMID: 21151105 [PubMed - as supplied by publisher]

14.DNA methylation profiling identifies epigenetic differences between diabetes patients with ESRD and diabetes patients without nephropathy.
Sapienza C, Lee J, Powell J, Erinle O, Yafai F, Reichert J, Siraj ES, Madaio M.
Epigenetics. 2011 Jan 1;6(1). [Epub ahead of print]
PMID: 21150313 [PubMed - as supplied by publisher]

15.Hypermethylation of multiple tumor-related genes associated with DMNT3b up-regulation served as a biomarker for early diagnosis of esophageal squamous cell carcinoma.
Li B, Wang B, Niu LJ, Jiang L, Qiu CC.
Epigenetics. 2011 Mar 1;6(3). [Epub ahead of print]
PMID: 21150312 [PubMed - as supplied by publisher]

16.Identification of genes required for de novo DNA methylation in Arabidopsis.
Greenberg MV, Ausin I, Chan SW, Cokus SJ, Cuperus JT, Feng S, Law JA, Chu C, Pellegrini M, Carrington JC, Jacobsen SE.
Epigenetics. 2011 Mar 1;6(3). [Epub ahead of print]
PMID: 21150311 [PubMed - as supplied by publisher] Free Article

17.Reactivation of L1 retrotransposon by benzo(a)pyrene involves complex genetic and epigenetic regulation.
Teneng I, Montoya-Durango DE, Quertermous JL, Lacy ME, Ramos KS.
Epigenetics. 2011 Mar 1;6(3). [Epub ahead of print]
PMID: 21150308 [PubMed - as supplied by publisher]

18.Autoinhibition of DNA cleavage mediated by RAG1 and RAG2 is overcome by an epigenetic signal in V(D)J recombination.
Grundy GJ, Yang W, Gellert M.
Proc Natl Acad Sci U S A. 2010 Dec 13. [Epub ahead of print]
PMID: 21149691 [PubMed - as supplied by publisher]

19.Rapid DNA-protein cross-linking and strand scission by an abasic site in a nucleosome core particle.
Sczepanski JT, Wong RS, McKnight JN, Bowman GD, Greenberg MM.
Proc Natl Acad Sci U S A. 2010 Dec 13. [Epub ahead of print]
PMID: 21149689 [PubMed - as supplied by publisher]

20.Domains of Tra1 important for activator recruitment and transcription coactivator functions of SAGA and NuA4 complexes.
Knutson BA, Hahn S.
Mol Cell Biol. 2010 Dec 13. [Epub ahead of print]
PMID: 21149579 [PubMed - as supplied by publisher]

21.HBO1 is required for H3K14 acetylation and normal transcriptional activity during embryonic development.
Kueh AJ, Dixon MP, Voss AK, Thomas T.
Mol Cell Biol. 2010 Dec 13. [Epub ahead of print]
PMID: 21149574 [PubMed - as supplied by publisher]

22.The cell biology of disease: FSHD: copy number variations on the theme of muscular dystrophy.
Cabianca DS, Gabellini D.
J Cell Biol. 2010 Dec 13;191(6):1049-60.
PMID: 21149563 [PubMed - in process]

23.Suppression of p53 activity through the cooperative action of Ski and histone deacetylase SIRT1.
Inoue Y, Iemura SI, Natsume T, Miyazawa K, Imamura T.
J Biol Chem. 2010 Dec 13. [Epub ahead of print]
PMID: 21149449 [PubMed - as supplied by publisher] Free Article

24.FoxO1 mediates an auto-feedback loop regulating SIRT1 expression.
Xiong S, Salazar G, Patrushev N, Alexander RW.
J Biol Chem. 2010 Dec 13. [Epub ahead of print]
PMID: 21149440 [PubMed - as supplied by publisher] Free Article

25.LSH and G9a/GLP complex are required for developmentally programmed DNA methylation.
Myant K, Termanis A, Sundaram AY, Boe T, Li C, Merusi C, Burrage J, de Las Heras JI, Stancheva I.
Genome Res. 2010 Dec 13. [Epub ahead of print]
PMID: 21149390 [PubMed - as supplied by publisher] Free Article

26.The novel metastasis promoter Merm1/Wbscr22 enhances tumor cell survival in the vasculature by suppressing Zac1/p53-dependent apoptosis.
Nakazawa Y, Arai H, Fujita N.
Cancer Res. 2010 Dec 10. [Epub ahead of print]
PMID: 21148752 [PubMed - as supplied by publisher]

27.JHDM3A module as an effector molecule in guide-directed modification of target chromatin.
Jeong YS, Park JS, Ko Y, Kang YK.
J Biol Chem. 2010 Dec 10. [Epub ahead of print]
PMID: 21148561 [PubMed - as supplied by publisher] Free Article

28.Lucanthone: A novel inhibitor of autophagy that induces cathepsin D-mediated apoptosis.
Carew JS, Espitia CM, Esquivel JA 2nd, Mahalingam D, Kelly KR, Reddy G, Giles FJ, Nawrocki ST.
J Biol Chem. 2010 Dec 10. [Epub ahead of print]
PMID: 21148553 [PubMed - as supplied by publisher] Free Article

29.Direct Conversion of C. elegans Germ Cells into Specific Neuron Types.
Tursun B, Patel T, Kratsios P, Hobert O.
Science. 2010 Dec 9. [Epub ahead of print]
PMID: 21148348 [PubMed - as supplied by publisher]

30.Deacetylation of the DNA-binding domain regulates p53-mediated apoptosis.
Mellert HS, Stanek TJ, Sykes SM, Rauscher FJ 3rd, Schultz DC, McMahon SB.
J Biol Chem. 2010 Dec 9. [Epub ahead of print]
PMID: 21148320 [PubMed - as supplied by publisher] Free Article

31.CDK-mediated phosphorylation of RBP1 and pRb promotes their dissociation to mediate release of the SAP30/mSin3/HDAC transcriptional repressor complex.
Suryadinata R, Sadowski M, Steel R, Sarcevic B.
J Biol Chem. 2010 Dec 9. [Epub ahead of print]
PMID: 21148318 [PubMed - as supplied by publisher] Free Article

32.Homocysteine suppresses the expression of the collagen cross-linker lysyl oxidase involving IL-6, Fli1 and epigenetic DNA-methylation.
Thaler R, Agsten M, Spitzer S, Paschalis EP, Karlic H, Klaushofer K, Varga F.
J Biol Chem. 2010 Dec 9. [Epub ahead of print]
PMID: 21148317 [PubMed - as supplied by publisher] Free Article

33.Histone and TK0471/TrmBL2 form a novel heterogeneous genome architecture in the hyperthermophilic archaeon Thermococcus kodakarensis.
Maruyama H, Shin M, Oda T, Matsumi R, Ohniwa RL, Itoh T, Shirahige K, Imanaka T, Atomi H, Yoshimura SH, Takeyasu K.
Mol Biol Cell. 2010 Dec 9. [Epub ahead of print]
PMID: 21148291 [PubMed - as supplied by publisher] Free Article

34.MDC1 cleavage by caspase-3: a novel mechanism for inactivating the DNA damage response during apoptosis.
Solier S, Pommier Y.
Cancer Res. 2010 Dec 8. [Epub ahead of print]
PMID: 21148072 [PubMed - as supplied by publisher]

35.Three dimensional collagen I promotes gemcitabine resistance in pancreatic cancer through MT1-MMP-mediated expression of HMGA2.
Dangi-Garimella S, Krantz SB, Barron MR, Shields MA, Heiferman M, Grippo PJ, Bentrem DJ, Munshi HG.
Cancer Res. 2010 Dec 8. [Epub ahead of print]
PMID: 21148071 [PubMed - as supplied by publisher]

Bodily JM, Mehta KP, Laimins LA.
Cancer Res. 2010 Dec 8. [Epub ahead of print]
PMID: 21148070 [PubMed - as supplied by publisher]

37.Conserved Antagonism between JMJD2A/KDM4A and HP1γ during Cell Cycle Progression.
Black JC, Allen A, Van Rechem C, Forbes E, Longworth M, Tschöp K, Rinehart C, Quiton J, Walsh R, Smallwood A, Dyson NJ, Whetstine JR.
Mol Cell. 2010 Dec 10;40(5):736-48.
PMID: 21145482 [PubMed - in process]

38.Epigenetic Instability due to Defective Replication of Structured DNA.
Sarkies P, Reams C, Simpson LJ, Sale JE.
Mol Cell. 2010 Dec 10;40(5):703-13.
PMID: 21145480 [PubMed - in process]

39.The chromatin signaling pathway: diverse mechanisms of recruitment of histone-modifying enzymes and varied biological outcomes.
Smith E, Shilatifard A.
Mol Cell. 2010 Dec 10;40(5):689-701.
PMID: 21145479 [PubMed - in process]

40.Histone demethylation and timely DNA replication.
Gerace EL, Moazed D.
Mol Cell. 2010 Dec 10;40(5):683-4.
PMID: 21145476 [PubMed - in process]

41.Heterochromatin replication: better late than ever.
Su TT.
Curr Biol. 2010 Dec 7;20(23):R1018-20.
PMID: 21145016 [PubMed - in process]

42.An E3 ubiquitin ligase prevents ectopic localization of the centromeric histone H3 variant via the centromere targeting domain.
Ranjitkar P, Press MO, Yi X, Baker R, MacCoss MJ, Biggins S.
Mol Cell. 2010 Nov 12;40(3):455-64.
PMID: 21070971 [PubMed - indexed for MEDLINE]

43.Psh1 is an E3 ubiquitin ligase that targets the centromeric histone variant Cse4.
Hewawasam G, Shivaraju M, Mattingly M, Venkatesh S, Martin-Brown S, Florens L, Workman JL, Gerton JL.
Mol Cell. 2010 Nov 12;40(3):444-54.
PMID: 21070970 [PubMed - indexed for MEDLINE]

44.Analysis of active and inactive X chromosome architecture reveals the independent organization of 30 nm and large-scale chromatin structures.
Naughton C, Sproul D, Hamilton C, Gilbert N.
Mol Cell. 2010 Nov 12;40(3):397-409.
PMID: 21070966 [PubMed - indexed for MEDLINE]

45.Mec1 is one of multiple kinases that prime the Mcm2-7 helicase for phosphorylation by Cdc7.
Randell JC, Fan A, Chan C, Francis LI, Heller RC, Galani K, Bell SP.
Mol Cell. 2010 Nov 12;40(3):353-63.
PMID: 21070963 [PubMed - indexed for MEDLINE]

46.An age of fewer histones.
Oberdoerffer P.
Nat Cell Biol. 2010 Nov;12(11):1029-31. No abstract available.
PMID: 21045802 [PubMed - indexed for MEDLINE]

47.Nucleosome-interacting proteins regulated by DNA and histone methylation.
Bartke T, Vermeulen M, Xhemalce B, Robson SC, Mann M, Kouzarides T.
Cell. 2010 Oct 29;143(3):470-84.
PMID: 21029866 [PubMed - indexed for MEDLINE]

48.ATR-X syndrome protein targets tandem repeats and influences allele-specific expression in a size-dependent manner.
Law MJ, Lower KM, Voon HP, Hughes JR, Garrick D, Viprakasit V, Mitson M, De Gobbi M, Marra M, Morris A, Abbott A, Wilder SP, Taylor S, Santos GM, Cross J, Ayyub H, Jones S, Ragoussis J, Rhodes D, Dunham I, Higgs DR, Gibbons RJ.
Cell. 2010 Oct 29;143(3):367-78.
PMID: 21029860 [PubMed - indexed for MEDLINE]

49.Fine-scale recombination rate differences between sexes, populations and individuals.
Kong A, Thorleifsson G, Gudbjartsson DF, Masson G, Sigurdsson A, Jonasdottir A, Walters GB, Jonasdottir A, Gylfason A, Kristinsson KT, Gudjonsson SA, Frigge ML, Helgason A, Thorsteinsdottir U, Stefansson K.
Nature. 2010 Oct 28;467(7319):1099-103.
PMID: 20981099 [PubMed - indexed for MEDLINE]

50.Neutrophil elastase and myeloperoxidase regulate the formation of neutrophil extracellular traps.
Papayannopoulos V, Metzler KD, Hakkim A, Zychlinsky A.
J Cell Biol. 2010 Nov 1;191(3):677-91. Epub 2010 Oct 25.
PMID: 20974816 [PubMed - indexed for MEDLINE]

51.Rec8-containing cohesin maintains bivalents without turnover during the growing phase of mouse oocytes.
Tachibana-Konwalski K, Godwin J, van der Weyden L, Champion L, Kudo NR, Adams DJ, Nasmyth K.
Genes Dev. 2010 Nov 15;24(22):2505-16. Epub 2010 Oct 22.
PMID: 20971813 [PubMed - indexed for MEDLINE] Free PMC Article Free text

52.Mediation of CTCF transcriptional insulation by DEAD-box RNA-binding protein p68 and steroid receptor RNA activator SRA.
Yao H, Brick K, Evrard Y, Xiao T, Camerini-Otero RD, Felsenfeld G.
Genes Dev. 2010 Nov 15;24(22):2543-55. Epub 2010 Oct 21.
PMID: 20966046 [PubMed - indexed for MEDLINE]

53.Chronic high-fat diet in fathers programs β-cell dysfunction in female rat offspring.
Ng SF, Lin RC, Laybutt DR, Barres R, Owens JA, Morris MJ.
Nature. 2010 Oct 21;467(7318):963-6.
PMID: 20962845 [PubMed - indexed for MEDLINE]

54.Metabolic disorders: Fathers’ nutritional legacy.
Skinner MK.
Nature. 2010 Oct 21;467(7318):922-3. No abstract available.
PMID: 20962833 [PubMed - indexed for MEDLINE]

55.How to separate entangled sisters: interplay between condensin and decatenase.
Hirano T.
Proc Natl Acad Sci U S A. 2010 Nov 2;107(44):18749-50. Epub 2010 Oct 20. No abstract available.
PMID: 20962275 [PubMed - indexed for MEDLINE]

56.The histone H4 Lys 20 methyltransferase PR-Set7 regulates replication origins in mammalian cells.
Tardat M, Brustel J, Kirsh O, Lefevbre C, Callanan M, Sardet C, Julien E.
Nat Cell Biol. 2010 Nov;12(11):1086-93. Epub 2010 Oct 17.
PMID: 20953199 [PubMed - indexed for MEDLINE]

57.PiggyBac transposon mutagenesis: a tool for cancer gene discovery in mice.
Rad R, Rad L, Wang W, Cadinanos J, Vassiliou G, Rice S, Campos LS, Yusa K, Banerjee R, Li MA, de la Rosa J, Strong A, Lu D, Ellis P, Conte N, Yang FT, Liu P, Bradley A.
Science. 2010 Nov 19;330(6007):1104-7. Epub 2010 Oct 14.
PMID: 20947725 [PubMed - indexed for MEDLINE]

58.xnd-1 regulates the global recombination landscape in Caenorhabditis elegans.
Wagner CR, Kuervers L, Baillie DL, Yanowitz JL.
Nature. 2010 Oct 14;467(7317):839-43.
PMID: 20944745 [PubMed - indexed for MEDLINE]

59.Local DNA hypomethylation activates genes in rice endosperm.
Zemach A, Kim MY, Silva P, Rodrigues JA, Dotson B, Brooks MD, Zilberman D.
Proc Natl Acad Sci U S A. 2010 Oct 26;107(43):18729-34. Epub 2010 Oct 11.
PMID: 20937895 [PubMed - indexed for MEDLINE] Free PMC Article Free text

60.SET DOMAIN GROUP2 is the major histone H3 lysine 4 trimethyltransferase in Arabidopsis.
Guo L, Yu Y, Law JA, Zhang X.
Proc Natl Acad Sci U S A. 2010 Oct 26;107(43):18557-62. Epub 2010 Oct 11.
PMID: 20937886 [PubMed - indexed for MEDLINE] Free PMC Article Free text

61.Genome-wide distribution of macroH2A1 histone variants in mouse liver chromatin.
Changolkar LN, Singh G, Cui K, Berletch JB, Zhao K, Disteche CM, Pehrson JR.
Mol Cell Biol. 2010 Dec;30(23):5473-83. Epub 2010 Oct 11.
PMID: 20937776 [PubMed - indexed for MEDLINE]

62.Heterogeneous myocyte enhancer factor-2 (Mef2) activation in myocytes predicts focal scarring in hypertrophic cardiomyopathy.
Konno T, Chen D, Wang L, Wakimoto H, Teekakirikul P, Nayor M, Kawana M, Eminaga S, Gorham JM, Pandya K, Smithies O, Naya FJ, Olson EN, Seidman JG, Seidman CE.
Proc Natl Acad Sci U S A. 2010 Oct 19;107(42):18097-102. Epub 2010 Oct 5.
PMID: 20923879 [PubMed - indexed for MEDLINE]

63.Escherichia coli condensin MukB stimulates topoisomerase IV activity by a direct physical interaction.
Li Y, Stewart NK, Berger AJ, Vos S, Schoeffler AJ, Berger JM, Chait BT, Oakley MG.
Proc Natl Acad Sci U S A. 2010 Nov 2;107(44):18832-7. Epub 2010 Oct 4.
PMID: 20921377 [PubMed - indexed for MEDLINE]

64.Nucleosome depletion at yeast terminators is not intrinsic and can occur by a transcriptional mechanism linked to 3′-end formation.
Fan X, Moqtaderi Z, Jin Y, Zhang Y, Liu XS, Struhl K.
Proc Natl Acad Sci U S A. 2010 Oct 19;107(42):17945-50. Epub 2010 Oct 4.
PMID: 20921369 [PubMed - indexed for MEDLINE]

65.Circadian CLOCK histone acetyl transferase localizes at ND10 nuclear bodies and enables herpes simplex virus gene expression.
Kalamvoki M, Roizman B.
Proc Natl Acad Sci U S A. 2010 Oct 12;107(41):17721-6. Epub 2010 Sep 27.
PMID: 20876123 [PubMed - indexed for MEDLINE]

66.Impact of natural genetic variation on the transcriptome of autotetraploid Arabidopsis thaliana.
Yu Z, Haberer G, Matthes M, Rattei T, Mayer KF, Gierl A, Torres-Ruiz RA.
Proc Natl Acad Sci U S A. 2010 Oct 12;107(41):17809-14. Epub 2010 Sep 27.
PMID: 20876110 [PubMed - indexed for MEDLINE]

67.Global effects of the small RNA biogenesis machinery on the Arabidopsis thaliana transcriptome.
Laubinger S, Zeller G, Henz SR, Buechel S, Sachsenberg T, Wang JW, Rätsch G, Weigel D.
Proc Natl Acad Sci U S A. 2010 Oct 12;107(41):17466-73. Epub 2010 Sep 24.
PMID: 20870966 [PubMed - indexed for MEDLINE] Free PMC Article Free text

68.Epigenetic modifications on X chromosomes in marsupial and monotreme mammals and implications for evolution of dosage compensation.
Rens W, Wallduck MS, Lovell FL, Ferguson-Smith MA, Ferguson-Smith AC.
Proc Natl Acad Sci U S A. 2010 Oct 12;107(41):17657-62. Epub 2010 Sep 22.
PMID: 20861449 [PubMed - indexed for MEDLINE] Free PMC Article Free text

69.CBP/p300 double null cells reveal effect of coactivator level and diversity on CREB transactivation.
Kasper LH, Lerach S, Wang J, Wu S, Jeevan T, Brindle PK.
EMBO J. 2010 Nov 3;29(21):3660-72. Epub 2010 Sep 21.
PMID: 20859256 [PubMed - indexed for MEDLINE]

70.Cks1, Cdk1, and the 19S proteasome collaborate to regulate gene induction-dependent nucleosome eviction in yeast.
Chaves S, Baskerville C, Yu V, Reed SI.
Mol Cell Biol. 2010 Nov;30(22):5284-94. Epub 2010 Sep 20.
PMID: 20855529 [PubMed - indexed for MEDLINE]

71.Unique DNA methylation patterns distinguish noninvasive and invasive urothelial cancers and establish an epigenetic field defect in premalignant tissue.
Wolff EM, Chihara Y, Pan F, Weisenberger DJ, Siegmund KD, Sugano K, Kawashima K, Laird PW, Jones PA, Liang G.
Cancer Res. 2010 Oct 15;70(20):8169-78. Epub 2010 Sep 14.
PMID: 20841482 [PubMed - indexed for MEDLINE]

72.Dynamic plasticity of large-scale chromatin structure revealed by self-assembly of engineered chromosome regions.
Sinclair P, Bian Q, Plutz M, Heard E, Belmont AS.
J Cell Biol. 2010 Sep 6;190(5):761-76.
PMID: 20819934 [PubMed - indexed for MEDLINE]

73.Loss of H3 K79 trimethylation leads to suppression of Rtt107-dependent DNA damage sensitivity through the translesion synthesis pathway.
Lévesque N, Leung GP, Fok AK, Schmidt TI, Kobor MS.
J Biol Chem. 2010 Nov 5;285(45):35113-22. Epub 2010 Sep 1.
PMID: 20810656 [PubMed - indexed for MEDLINE]

74.MLL2 is required in oocytes for bulk histone 3 lysine 4 trimethylation and transcriptional silencing.
Andreu-Vieyra CV, Chen R, Agno JE, Glaser S, Anastassiadis K, Stewart AF, Matzuk MM.
PLoS Biol. 2010 Aug 17;8(8). pii: e1000453.
PMID: 20808952 [PubMed - indexed for MEDLINE] Free PMC Article Free text

75.O-GlcNAc transferase regulates mitotic chromatin dynamics.
Sakabe K, Hart GW.
J Biol Chem. 2010 Nov 5;285(45):34460-8. Epub 2010 Aug 30.
PMID: 20805223 [PubMed - indexed for MEDLINE]

76.Heat shock transcription factor 1 localizes to sex chromatin during meiotic repression.
Akerfelt M, Vihervaara A, Laiho A, Conter A, Christians ES, Sistonen L, Henriksson E.
J Biol Chem. 2010 Nov 5;285(45):34469-76. Epub 2010 Aug 27.
PMID: 20802198 [PubMed - indexed for MEDLINE] Free Article

77.Synergistic chemosensitivity of triple-negative breast cancer cell lines to poly(ADP-Ribose) polymerase inhibition, gemcitabine, and cisplatin.
Hastak K, Alli E, Ford JM.
Cancer Res. 2010 Oct 15;70(20):7970-80. Epub 2010 Aug 26.
PMID: 20798217 [PubMed - indexed for MEDLINE]

78.Expanding role of the jumonji C domain as an RNA hydroxylase.
Noma A, Ishitani R, Kato M, Nagao A, Nureki O, Suzuki T.
J Biol Chem. 2010 Nov 5;285(45):34503-7. Epub 2010 Aug 25.
PMID: 20739293 [PubMed - indexed for MEDLINE]

79.Nucleosome interactions and stability in an ordered nucleosome array model system.
Blacketer MJ, Feely SJ, Shogren-Knaak MA.
J Biol Chem. 2010 Nov 5;285(45):34597-607. Epub 2010 Aug 25.
PMID: 20739276 [PubMed - indexed for MEDLINE]

80.Characterization of a novel WDR5-binding site that recruits RbBP5 through a conserved motif to enhance methylation of histone H3 lysine 4 by mixed lineage leukemia protein-1.
Odho Z, Southall SM, Wilson JR.
J Biol Chem. 2010 Oct 22;285(43):32967-76. Epub 2010 Aug 17.
PMID: 20716525 [PubMed - indexed for MEDLINE]

81.Histone Sin mutations promote nucleosome traversal and histone displacement by RNA polymerase II.
Hsieh FK, Fisher M, Ujvári A, Studitsky VM, Luse DS.
EMBO Rep. 2010 Sep;11(9):705-10. Epub 2010 Aug 13.
PMID: 20706221 [PubMed - indexed for MEDLINE]

82.Physical and functional interaction between the condensin MukB and the decatenase topoisomerase IV in Escherichia coli.
Hayama R, Marians KJ.
Proc Natl Acad Sci U S A. 2010 Nov 2;107(44):18826-31. Epub 2010 Aug 9.
PMID: 20696938 [PubMed - indexed for MEDLINE]

83.Rod/Zw10 complex is required for PIASy-dependent centromeric SUMOylation.
Ryu H, Azuma Y.
J Biol Chem. 2010 Oct 15;285(42):32576-85. Epub 2010 Aug 9.
PMID: 20696768 [PubMed - indexed for MEDLINE]

84.Breast cancer DNA methylation profiles are associated with tumor size and alcohol and folate intake.
Christensen BC, Kelsey KT, Zheng S, Houseman EA, Marsit CJ, Wrensch MR, Wiemels JL, Nelson HH, Karagas MR, Kushi LH, Kwan ML, Wiencke JK.
PLoS Genet. 2010 Jul 29;6(7):e1001043.
PMID: 20686660 [PubMed - indexed for MEDLINE] Free PMC Article Free text

85.Nucleotide supply, not local histone acetylation, sets replication origin usage in transcribed regions.
Gay S, Lachages AM, Millot GA, Courbet S, Letessier A, Debatisse M, Brison O.
EMBO Rep. 2010 Sep;11(9):698-704. Epub 2010 Jul 30.
PMID: 20671737 [PubMed - indexed for MEDLINE]

86.SUMOylation modulates the function of Aurora-B kinase.
Fernández-Miranda G, Pérez de Castro I, Carmena M, Aguirre-Portolés C, Ruchaud S, Fant X, Montoya G, Earnshaw WC, Malumbres M.
J Cell Sci. 2010 Aug 15;123(Pt 16):2823-33. Epub 2010 Jul 27.
PMID: 20663916 [PubMed - indexed for MEDLINE]

87.Drosophila CAF-1 regulates HP1-mediated epigenetic silencing and pericentric heterochromatin stability.
Huang H, Yu Z, Zhang S, Liang X, Chen J, Li C, Ma J, Jiao R.
J Cell Sci. 2010 Aug 15;123(Pt 16):2853-61. Epub 2010 Jul 27.
PMID: 20663913 [PubMed - indexed for MEDLINE]

88.Changes in chromatin structure during processing of wax-embedded tissue sections.
Kerr E, Kiyuna T, Boyle S, Saito A, Thomas JS, Bickmore WA.
Chromosome Res. 2010 Sep;18(6):677-88. Epub 2010 Jul 27.
PMID: 20661639 [PubMed - indexed for MEDLINE] Free PMC Article Free text

89.Inter- and intra-individual variation in allele-specific DNA methylation and gene expression in children conceived using assisted reproductive technology.
Turan N, Katari S, Gerson LF, Chalian R, Foster MW, Gaughan JP, Coutifaris C, Sapienza C.
PLoS Genet. 2010 Jul 22;6(7):e1001033.
PMID: 20661447 [PubMed - indexed for MEDLINE] Free PMC Article Free text

90.Rad3 decorates critical chromosomal domains with gammaH2A to protect genome integrity during S-Phase in fission yeast.
Rozenzhak S, Mejía-Ramírez E, Williams JS, Schaffer L, Hammond JA, Head SR, Russell P.
PLoS Genet. 2010 Jul 22;6(7):e1001032.
PMID: 20661445 [PubMed - indexed for MEDLINE] Free PMC Article Free text

91.Structural maintenance of chromosomes (SMC) proteins promote homolog-independent recombination repair in meiosis crucial for germ cell genomic stability.
Bickel JS, Chen L, Hayward J, Yeap SL, Alkers AE, Chan RC.
PLoS Genet. 2010 Jul 22;6(7):e1001028.
PMID: 20661436 [PubMed - indexed for MEDLINE] Free PMC Article Free text

92.Acetylation-dependent oncogenic activity of metastasis-associated protein 1 co-regulator.
Ohshiro K, Rayala SK, Wigerup C, Pakala SB, Natha RS, Gururaj AE, Molli PR, Månsson SS, Ramezani A, Hawley RG, Landberg G, Lee NH, Kumar R.
EMBO Rep. 2010 Sep;11(9):691-7. Epub 2010 Jul 23.
PMID: 20651739 [PubMed - indexed for MEDLINE]

93.Relocation of the chromosomal passenger complex prevents mitotic checkpoint engagement at anaphase.
Vázquez-Novelle MD, Petronczki M.
Curr Biol. 2010 Aug 10;20(15):1402-7. Epub 2010 Jul 8.
PMID: 20619651 [PubMed - indexed for MEDLINE]

94.Contrasting chromatin organization of CpG islands and exons in the human genome.
Choi JK.
Genome Biol. 2010;11(7):R70. Epub 2010 Jul 5.
PMID: 20602769 [PubMed - indexed for MEDLINE] Free PMC Article Free text

95.Locus co-occupancy, nucleosome positioning, and H3K4me1 regulate the functionality of FOXA2-, HNF4A-, and PDX1-bound loci in islets and liver.
Hoffman BG, Robertson G, Zavaglia B, Beach M, Cullum R, Lee S, Soukhatcheva G, Li L, Wederell ED, Thiessen N, Bilenky M, Cezard T, Tam A, Kamoh B, Birol I, Dai D, Zhao Y, Hirst M, Verchere CB, Helgason CD, Marra MA, Jones SJ, Hoodless PA.
Genome Res. 2010 Aug;20(8):1037-51. Epub 2010 Jun 15.
PMID: 20551221 [PubMed - indexed for MEDLINE] Free PMC Article Free text

96.Control of ciliogenesis by FOR20, a novel centrosome and pericentriolar satellite protein.
Sedjaï F, Acquaviva C, Chevrier V, Chauvin JP, Coppin E, Aouane A, Coulier F, Tolun A, Pierres M, Birnbaum D, Rosnet O.
J Cell Sci. 2010 Jul 15;123(Pt 14):2391-401. Epub 2010 Jun 15. Erratum in: J Cell Sci. 2010 Jul 15;123(Pt 14):2521.
PMID: 20551181 [PubMed - indexed for MEDLINE]

97.Distinct contributions of conserved modules to Runt transcription factor activity.
Walrad PB, Hang S, Joseph GS, Salas J, Gergen JP.
Mol Biol Cell. 2010 Jul;21(13):2315-26. Epub 2010 May 12.
PMID: 20462957 [PubMed - indexed for MEDLINE] Free PMC Article Free text

98.P38 mitogen-activated protein kinase activity is required during mitosis for timely satisfaction of the mitotic checkpoint but not for the fidelity of chromosome segregation.
Lee K, Kenny AE, Rieder CL.
Mol Biol Cell. 2010 Jul;21(13):2150-60. Epub 2010 May 12.
PMID: 20462950 [PubMed - indexed for MEDLINE] Free PMC Article Free text

99.Interaction of thyroid hormone with histone from calf thymus nuclei.
Tabachnick M, Giorgio NA Jr.
Nature. 1966 Dec 31;212(5070):1610-1. No abstract available.
PMID: 21105538 [PubMed - indexed for MEDLINE]

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